The European Federation for Medicinal Chemistry (EFMC) is an independent association representing medicinal chemistry societies in Europe. Its objective is to advance the science of medicinal chemistry by promoting cooperation and networking, by providing training and mentoring, by rewarding scientific excellence, and by facilitating communication and influencing stakeholders.

Meetings  September 2016 Next

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"Can Science Save the Day ?" - A Public Engagement Event at EFMC-ISMC

At the occasion of the XXIV EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC), a Public Engagement Event has been organised in order to raise the awareness of the General Public on the research in the pharmaceutical industry.

The event took place at the Manchester Museum of Science and Industry and took the format of an expert panel (Allan Jordan, Eric Kerran, Derek Lowe, Vicky Steadman) “pitching" for funding for key healthcare problems e.g cancer, infectious diseases dementia. Each outlined why their area was in need of new advances and medicines.

This was a catalyst for the audience to discuss these topics and to ask the panel questions. With many members of the general public in the audience it was great to see the level of engagement and interest.  There were some great insights provided by patients and carers.

This was all expertly (and entertainingly) chaired by Renee Watson.  A great, thought-provoking evening was had by all.

The EFMC wanted to thank the EFMC-ISMC 2016 Local Organising Committee for having organised this ground-breaking public event.

Photographer - Fabien Venturi
Contact: venturifab@yahoo.fr


EFMC Press Conference at EFMC-ISMC 2016

In its effort to constantly foster the visibility and recognition of Medicinal Chemistry and following two positive experience at the EFMC-ISMC 2014 in Lisbon and the Frontiers Meeting 2015 in Antwerp, the EFMC took once again the opportunity of its flagship meeting, the XXIV EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC) to host a third press conference where local newspaper, scientific press and one reporter of the Radio Podcast Show "The Naked Scientists" were present. 4 keynote speakers gave their view on the importance of the discipline and the key theme for this year "MedChem impact/importance, collaborative nature of medicinal chemistry/drug discovery".

Keynote Speakers:

  • Michael Sofia (Arbutus Biopharma, United States)
  • Joe Kozlowski (Merck, Sharp & Dohme, United States)
  • Nicolas Soldermann (Novartis, Switzerland)
  • John Liddle (GlaxoSmithKline, United Kingdom)

Fabrizio Giordanetto (D.E. Shaw Research LLC, United States), leader of the EFMC Working Group on "Visibility and Recognition of Medicinal Chemistry" chaired the Press Conference.

Koen Augustyns, EFMC President, was invited to give the introdruction speech and stressed the importance of international cooperation - mentioning the recently organised STOA Working Breakfast and the Signature of a Memorandum of Understanding between the EFMC and the CPA.

Photographer - Fabien Venturi
Contact: venturifab@yahoo.fr


Signature of a Memorandum of Understanding between EFMC & CPA

At the occasion of the XXIV EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC), held in Manchester on August 28 - September 1, 2016, the European Federation for Medicinal Chemistry (EFMC) and the Chinese Pharmaceutical Association (CPA) signed a Memorandum of Understanding with the intent to establish a collaborative and sustainable relationship.

"The mission of the European Federation for Medicinal Chemistry (EFMC) is to advance and promote the science of medicinal chemistry by promoting collaboration and networking, providing training and mentoring, rewarding scientific excellence, facilitating communication and influencing stakeholders. The EFMC-International Symposium on Medicinal Chemistry (EFMC-ISMC) held in Manchester is the EFMC’s flagship meeting that contributed perfectly to this mission. Of course, such a mission can not be fulfilled alone. Therefore, EFMC is collaborating with its national adhering organisations and other learned societies such as the Medicinal Chemistry Division of the American Chemical Society (ACSMEDI), EuCheMS and the Asian Federation for Medicinal Chemistry (AFMC). In that respect, EFMC is extremely pleased to sign today a Memorandum of Understanding with the Chinese Pharmaceutical Association (CPA). CPA is a very large and important society with a long history and a very strong division of medicinal chemistry. Medicinal Chemistry is clearly gaining momentum in China. This is exemplified in a recent paper published in the Journal of Medicinal Chemistry describing that the papers with a corresponding author in China have multiplied by 5 in the last ten years. The new collaboration between CPA and EFMC is therefore timely and we are looking forward to joint activities to promote and advance the science of medicinal chemistry."

The Memorandum of Understanding was signed during an official ceremony with EFMC and CPA officials and was followed by a gift exchange ceremony between Koen Augustyns, President of EFMC and Kaixian Chen, Vice-President of the CPA.

Photographer - Fabien Venturi
Contact: venturifab@yahoo.fr


EFMC Awards at EFMC-ISMC 2016

The 2016 EFMC Awards have been conferred on occasion of the XXIV EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC), held in Manchester on August 28 - September 1, 2016.

Nauta Award for Pharmacochemistry
Prof. François Diederich – ETH Zürich, Switzerland

For his outstanding contributions to the science of medicinal chemistry. Prof. François Diederich made essential contributions to the fundamental understanding of non-bonding interactions involved in molecular recognition and their application in modern drug design. His scientific work is documented in more than 700 publications and beautifully describes interactions such as sulfur-aromatics, cation-Pi, fluorine interactions and halogen bonding that are actively used by many scientists around the world in the discovery of novel drugs.

UCB-Ehrlich Award for Excellence in Medicinal Chemistry
Prof. Paul J. Hergenrother – University of Illinois at Urbana-Champaign, United States

For his groundbreaking work on procaspase-3 activation by a small molecule PAC-1, thereby inducing apoptosis in cancer cells. In his scientific research he uses natural products as starting points for complex molecule synthesis in an approach named “complexity-to-diversity”.  Next to basic research, he also aims to bring his novel compounds to the clinic for the benefit of patients.

Prous Institute-Overton and Meyer Award for New Technologies in Drug Discovery
Prof. Jan Steyaert – VIB & VU Brussels, Belgium

For his pioneering work in the field of nanobody-enabled structural biology. His nanobody technology led to X-ray crystallographic structures of GPCRs locked in an agonist-bound active conformational state and to the first view of a GPCR transmembrane signalling complex. These novel GPCR structures are now finding widespread use in the discovery of novel drugs.

Photographer - Fabien Venturi
Contact: venturifab@yahoo.fr


EFMC Prizes at EFMC-ISMC 2016

The « EFMC Prize for a Young Medicinal Chemist in Academia » and the « EFMC Prize for a Young medicinal chemist in Industry » have been established by the European Federation for Medicinal Chemistry (EFMC) to acknowledge and recognize an outstanding young medicinal chemist working in academia or in industry within Europe.The prizes are given annually and consist of a diploma, 1.000€ and an invitation for a short presentation at an EFMC Symposium. Two nominees are also identified and acknowledged.

The 2016 Prizes have been conferred on occasion of the XXIV EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC), held in Manchester on August 28 - September 1, 2016.

Winner of the Industry Prize was Jean QUANCARD (Novartis Pharma, Switzerland), gave a talk on the “INHIBITION OF THE COP9 SIGNALOSOME AS A NOVEL APPROACH TO TREAT CANCER”. The most meritorious runners-up were Nicolas Desroy (Galapagos, France) and Anne Valade (UCB, Belgium).

Frank BOECKLER (Eberhard Karls University Tuebingen, Germany) won the 2016 EFMC Prize for a Young Medicinal Chemist in Academia. At the EFMC-ISMC Symposium, he gave a talk entitled “SIGMA HOLE BONDING IN KINASE DRUG DISCOVERY“. Nathaniel Martin (Utrecht University, The Netherlands) and Sylvia Ortega Gutierrez (Universidad Complutense de Madrid, Spain) have been identified and acknowledged as runners-up.

Photographer - Fabien Venturi
Contact: venturifab@yahoo.fr


EFMC Roche Studentships

One of the goals of the EFMC is to enhance interactions at the industry/academia interface and to promote improved cooperation between the pharmaceutical industry and academia. EFMC and Roche therefore proposed an opportunity to broaden the awareness to European University based chemistry students of the EFMC activities by rewarding excellence accomplished during a medicinal chemistry internship in industry.

The third EFMC-Roche studentships have been announced by Koen Augustyns (EFMC) and Fionn O'Hara (HOFFMANN-LA ROCHE) at the XXIV EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC), held in Manchester on August 28 - September 1, 2016.

The recipients were Ana Isabel OLIVEIRA ALMEIDA (UNIVERSITY OF BIRMINGHAM, UK) and Niamh JIMENEZ (F. HOFFMANN-LA ROCHE, Switzerland). We would like to congratulate Ana Isabela and Niamh for their fantastic achievement.

EFMC would like to thank Roche for their contribution and support.

To find more about the EFMC Prizes and studentships, we invite you to visit the EFMC website www.efmc.info

Photographer - Fabien Venturi
Contact: venturifab@yahoo.fr


EFMC Best Poster Prize at EFMC-ISMC 2016

The EFMC Best Poster Prizes have been granted during the XXIV International Symposium on Medicinal Chemistry (EFMC-ISMC 2016) to the following participants :

  • P036 - Dmitrii Kalinin (University of Münster, Germany)
    DESIGN, SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF PROLINE HYDROXAMATES TARGETING ZINC-DEPENDENT ENZYMES
  • P096 - Yasuhiro Imaeda (Takeda Pharmaceutical Company, Japan)
    DISCOVERY OF TAK-272: A NOVEL, POTENT AND ORALLY ACTIVE RENIN INHIBITOR
  • P132 - Nis Halland (Sanofi, Germany)
    NOVEL SMALL MOLECULE INHIBITORS OF ACTIVATED THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFIa) FROM NATURAL PRODUCT ANABAENOPEPTIN
  • P192 - Geoffrey Schwertz (ETH Zurich, Switzerland)
    SHMT INHIBITION: A NEW HOPE TO DEFEAT MALARIA
  • P253 - Xavier Lucas (University of Dundee, United Kingdom)
    PROTACTING LEADS: DESIGN OF A PROTEIN SURFACE-TARGETING FRAGMENT LIBRARY
  • P334 - Jonas Kaindl (Friedrich-Alexander-University Erlangen-Nuernberg, Germany)
    STRUCTURE-GUIDED DEVELOPMENT AND MOLECULAR MODELLING OF D2R/NTS1R HETERODIMER-SELECTIVE LIGANDS
  • P444 - Arno Vermote (Ghent University, Belgium)
    POTENTIATOR DRUGS FOR BAD BUGS - HAMAMELITANNIN ANALOGUES POTENTIATE ANTIBIOTICS IN THE FIGHT AGAINST STAPHYLOCOCCUS AUREUS
  • P466 - Liam Hudson (Institute of Cancer Research, United Kingdom)
    DEVELOPMENT OF A NEW CLASS OF ALK2 INHIBITOR FOR THE STUDY OF THE MOST AGGRESSIVE PAEDIATRIC BRAIN CANCER, DIPG
  • P592 - Christian Kersten (Johannes Gutenberg University, Germany)
    SELECTIVITY DETERMINING FEATURES IN N-MYRISTOYLTRANSFERASES - A POTENTIAL DRUG TARGET WITH A HIGHLY CONSERVED BINDING SITE
  • P522 - Daniela Dengler (Friedrich-Alexander University Erlangen-Nuremberg, Germany)
    DISCOVERY OF A G-PROTEIN BIASED MU OPIOID ANALGESIC WITH REDUCED SIDE EFFECTS

Each Poster Prize consists of a Diploma and a 200€ cash prize

Photographer - Fabien Venturi
Contact: venturifab@yahoo.fr


EFMC-YMCS Prizes 2016

The 2016 EFMC-YMCS Prizes have been conferred on occasion of the 3rd Young Medicinal Chemist Symposium (EFMC-YMCS), held in Manchester on September 1-2, 2016.

Mr Freek JANSSEN (Leiden University, The Netherlands) received the EFMC-YMCS Presentation Prize for his presentation on the "Development of Highly Selective and Reversible Diacylglycerol Lipase Inhibitors ".The prize was awarded by Koen Augustyns - EFMC President on behalf of the prize sponsors EFMC & Actelion.

The Presentation Prize covers:

  • An oral communication and free registration for the next EFMC-ASMC'17 in Vienna in Summer 2017 (sponsored by the EFMC)
  • A travel grant of up to 1000€ to visit EFMC-ASMC'17 (sponsored by Actelion)

Ms Anna COOPER (University of Otago, New Zealand) received the EFMC-YMCS Poster Prize for her presentation on "Design, Synthesis and Pharmacological Evaluation of Fluorescent Tools for Studying Cannabinoid Type 2 Receptor". The prize was awarded by Dave Alker on behalf of the prize sponsors MedChemCom and Sir Simon Campbell. The Prize consists of a diploma, a £500 cash prize offered by Sir Simon Campbell and an e-subscription to MedChemComm.

Mr Piotr DRACZKOWSKI (University of Lublin, Poland) was awarded the EFMC-YMCS Public's Choice Prize for her presentation on "Experimental Platform for Characterization and High-Throughput Screening of Acetylcholinesterase Inhibitors". The prize, based on the votes of YMCS participants, was awarded by Fionn O'Hara (Roche) on behalf of the prize sponsor Roche. The Prize consists of a diploma and an iPad.


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