MedChemWatch
Monthly Newsletter April 2017

10th Joint Meeting on Medicinal Chemistry, June 25–28, 2017, Dubrovnik (Srebreno), Croatia

The JMMC is an important scientific event in the field of medicinal chemistry which gives the opportunity for networking of the participants coming mainly from the nine middle European countries: Austria, Croatia, Czech Republic, Greece, Hungary, Italy, Poland, Slovakia and Slovenia. This leads us to the principal aims of the Meeting: dissemination of research results, training of young researchers and enhancement of transnational collaborations between scientists from academia as well as industry. 

The 10th Joint Meeting on Medicinal Chemistry will be organized by the Medicinal Chemistry Section of the Croatian Chemical Society and sponsored by the European Federation for Medicinal Chemistry.

The JMMCs is an important scientific event in the field of medicinal chemistry which gives the opportunity for networking of the participants coming mainly from the nine middle European countries: Austria, Croatia, Czech Republic, Greece, Hungary, Italy, Poland, Slovakia and Slovenia. This leads us to the principal aims of the Meeting: dissemination of research results, training of young researchers and enhancement of transnational collaborations between scientists from academia as well as industry.  

The 10th JMMC will cover drug discovery advances in the major therapeutic areas, including anti-infectives, cardiovascular diseases, neurodegenerative diseases and oncology. JMMC 2017 will present various topics which will cover advances in approaches for hit findings and accelerating lead optimization process, exploration of new chemical entities from nature, discovery of small molecule chemical probes, optimization of drug delivery and computational medicinal chemistry. The intention is to get together scientists from different countries, disciplines and sectors, and in a relaxed atmosphere discuss and rationalize results and challenges associated with new drug discovery.

Topics

Meeting Unmet Medical Needs

  • Anti-infectives
  • Anticancer therapeutics
  • Neuroactive drugs

Advancing strategies in drug discovery and development

  • Computational medicinal chemistry
  • Discovery of small molecule probes
  • Epigenetics
  • New chemical entities from nature
  • Redox active targets and compounds

Early registration and abstract submission deadline: April 1

The speakers, as well as information on registration can be found on the symposium website.

17th Hellenic Symposium on Medicinal Chemistry, June 1-3, 2017, Thessaloniki, Greece

HSMC-17 continues the tradition of biannual meetings established since 30 years in Greece as a forum for the discussion of recent advances in the field of Medicinal Chemistry. Abstracts Submission deadline is approaching! (15th April 2017)

The Symposium is organized by the Hellenic Society of Medicinal Chemistry (HSMC) and the Department of Pharmaceutical Chemistry of the Faculty of Pharmacy, Aristotle University of Thessaloniki.

HSMC-17 continues the tradition of biannual meetings established since 30 years in Greece as a forum for the discussion of recent advances in the field of Medicinal Chemistry. The topics of the Symposium include Drug Design and lead identification and optimization, ADME/Tox properties in drug discovery, Advances in Synthetic Medicinal Chemistry, Natural Products, Chemical Biology, Pharmacology, Computational Chemistry, Chemoinformatics/Pharmaco-informatics, Pharmaceutical Analysis and –omics in Pharmaceutical Sciences.

The official language of the Symposium is English.

Thessaloniki, the capital of North Greece, is a fascinating city and cultural center, steeped in the Byzantine Era, where you can at the same time enjoy modern life style activities. The Symposium venue is located in the heart of Thessaloniki and easily accessible, offering to the participants the possibility to visit the most important historical sites such as White Tower, which is the symbol of the city, the International Trade Fair grounds, the Galerious Arch, the Rotonda, St. Dimitrios church, the Citadel and many others. Furthermore you can visit some places out of the city such as Vergina, the place where the tomb of Philip 2nd, King of Macedonia and Alexander’s the Great father was found, Dion, at mountain Olympus, where the ancient Greeks were celebrating their gods and Mountain Athos, where the autonomous Holy community of monks is located.

Abstracts Submission: 15th April 2017
Early Registration: till 30th April 2017

Information on registration can be found on the symposium website: http://helmedchem2017.gr/registration.html

1st RSC Anglo-Nordic Medicinal Chemistry Symposium, June 11-14, 2017, Copenhagen, Denmark

This symposium is the 1st Anglo-Nordic meeting organised by the Biological and Medicinal Chemistry Sector of the Royal Society of Chemistry with Nordic affiliates to showcase the very best medicinal chemistry. This conference is aimed at medicinal chemists at all career stages and promises to be an exciting and invigorating meeting packed with fantastic opportunities to disseminate knowledge and make new contacts.

The scientific programme will feature classical and contemporary themed lectures, focusing on medicinal chemistry and related technologies and disciplines across a range of drug targets and modalities. A distinguishing feature of this symposium is the collegiate conference style which encourages an atmosphere of information sharing and learning.

The event will include first rate lectures, poster session, trade exhibition, ample networking opportunities throughout meeting, conference welcome buffet on Sunday, optional social visit to Kronborg Castle, exceptional location, venue and accommodation.

Confirmed Speakers

  •     Mike Barker (GlaxoSmithKline, United Kingdom)
  •     Doug Beshore (Merck, United States)
  •     Kevin Neil Dack (LEO Pharma A/S, Denmark)
  •     Katherine Fenner (AstraZenca, United Kingdom)
  •     Christoph Gaul (Novartis, Switzerland)
  •     John Harling (GlaxoSmithKline, United Kingdom)
  •     Zoë Harrison (GlaxoSmithKline, United Kingdom)
  •     Anneli Nordqvist (AstraZeneca, Sweden)
  •     Gebhard Thoma (Novartis, Switzerland)
  •     Thomas Franch (Nuevolution, Denmark)
  •     Erik Daa Funder (Roche Innovation Center Copenhagen, Denmark)
  •     Jens Carlsson (Uppsala University, Sweden)
  •     Holger Monenschein (Takeda, United States)
  •     Richard Ward (AstraZeneca, United Kingdom)
  •     Trond Ulven (University of Southern Denmark, Denmark)
  •     Frank Lovering (Pfizer, United States)
  •     Harrie Gijsen (Janssen Pharmaceutica NV, Belgium)
  •     Steve Watson (Heptares, United Kingdom)
  •     Dan Teufel (Bicycle Therapeutics, United Kingdom)
  •     Kenneth Granberg (AstraZeneca, Sweden)
  •     James Scott (AstraZeneca, United Kingdom)

Information on registration can be found on the symposium website: http://www.rsc.org/events/detail/23370/1st-rsc-anglo-nordic-medicinal-chemistry-symposium

Winners and Runners-up for the EFMC Prizes announced!

The Selection Committees are proud to announce the names of the winners and the runners-up of the EFMC Prize for a Young Medicinal Chemist in Industry and in Academia.

EFMC Prize for a Young Medicinal Chemist in Industry

Philip Humphreys (GlaxoSmithKline, UK)
Fabien Lecomte (UCB, UK)
Mirjana Bukvic (Fidelta, Croatia)

“The EFMC Prize for Young Medicinal Chemist in Industry” acknowledges and recognizes an outstanding young medicinal chemist (<12 years after PhD) working in industry within Europe. The Prize is given annually and consists of a diploma, € 1.000 and an invitation for a short presentation at an EFMC symposium.

Philip Humphreys will give an oral communication at the 7th edition of the EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC’17) in Vienna, Austria, on August 28-31, 2017.

EFMC Prize for a Young Medicinal Chemist in Academia

Christian Gruber (Medical University of Vienna, Austria)
Andreas Koeberlee (Friedrich-Schiller-University Jena, Germany)
Vittorio Limongelli (USI Lugano, Switzerland)

“The EFMC Prize for Young Medicinal Chemist in Academia” acknowledges and recognizes an outstanding young medicinal chemist (<12 years after PhD) working in Academia within Europe. The Prize is given annually and consists of a diploma, € 1.000 and an invitation for a short presentation at an EFMC symposium.

Christian Gruber will give an oral communication at the 7th edition of the EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC’17) in Vienna, Austria, on August 28-31, 2017.

James E. Bradner will give the opening lecture at the upcoming EFMC-ASMC’17

James E. Bradner (President of the Novartis Institutes for BioMedical Research (NIBR), Cambridge, MA, United States) will give an inspiring talk on the Next-Generation Small Molecule Therapeutics as opening lecture of the upcoming 7th edition of the EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC’17) in Vienna, Austria, on August 28-31, 2017.

The symposium will bring together chemists from industry, academia and start-up companies from around the world and is focused on the most recent advances in new synthetic methodologies, total synthesis, fluorination approaches, bioisosteres and building blocks, chemical biology, medicinal chemistry, drug discovery and development leading to new or improved methods for the synthesis of pharmaceuticals. 

Beyond key lectures in synthetic and fluorination chemistry, as well as recent case studies in medicinal chemistry and drug discovery, the symposium aims at bridging the range from ‘small molecules’ to ‘large molecules’ including carbohydrates, natural products, novel protein scaffolds and genes; it is expected to attract experts in synthetic chemistry, medicinal chemistry, total synthesis, catalysis, drug discovery, molecular imaging, and chemical development.

The general concept of the meeting, with talks equally selected from industry and academia, will include an opening lecture, 26 invited lectures, 10 short communications selected from submitted abstracts and a large poster session and commercial exhibition.

Deadlines

  • April 10, 2017: Deadline for abstract submission for Oral Communication selection, free abstract submission for Poster presentation and Early Bird fees.
  • From April 10 until June 20, 2017: abstracts for Poster presentations can still be submitted, but are subject to the prior payment of 50,00€ handling fees.

Find out more on http://www.efmc-asmc.org

The EFMC Grant to attend the 13th EFMC Short Course has been awarded to...

Mr Arun Kumar Mahato (University of Helsinki, Finland) has received the EFMC Grant, covering half of the registration fee, to attend the upcoming 13th EFMC Short Course on Medicinal Chemistry: A Matter of Time: A Kinetic Perspective on Drug-Target Interactions, Oegstgeest (near Leiden), The Netherlands - April 23-26, 2017.

Every year, the EFMC is funding grants for its organised events with the aim to support the participation of young academic scientists.

The upcoming event(s) where an EFMC Grant can be applied for are: 

  • EFMC-ASMC'17 - International Symposium on Advances in Synthetic and Medicinal Chemistry 
    (deadline for application is April 10, 2017
    ) - Link to the Event
  • 4th EFMC Young Medicinal Chemist Symposium 
    (in combination with the EFMC-ASMC'17)
     - Link to the Event

The full list of event, application conditions and application form can be found on the website www.efmc.info.

ACS-MEDI call for MedChem Hall of Fame Nominations

The Medicinal Chemistry Hall of Fame honors medicinal chemists who have made outstanding contributions to medicinal chemistry through research, teaching, and/or division service. 

The Hall of Fame can be visited at www.acsmedchem.org/?nd=hof

The nomination procedure is available at www.acsmedchem.org/?nd=abouthof

Deadline for nominations is May 1.

EuCheMS is opening calls for several awards

EuCheMS is opening calls for the following award:

  • EuCheMS Award for Service
  • European Chemistry Gold Medal

  • The EuCheMS Award for Service acknowledges outstanding commitment with regard to fostering chemistry and molecular sciences in Europe and the goals of EuCheMS. In addition to recognized service to EuCheMS, this may include activities in governmental, non-governmental or funding organizations, publicity-related activities, etc. Nominations must demonstrate achievements for improved competitiveness, visibility, coherence or structure of chemistry in Europe.The nomination must demonstrate service to EuCheMS and/or to European chemistry over and above the basic voluntary contribution that would normally be expected.

    You will find on-line nomination form as well as additional information at http://www.euchems.eu/awards/award-for-service-new1/

    Deadline: 15 May 2017
  • The EuCheMS Award, the European Chemistry Gold Medal, for exceptional achievements in the field of chemistry in Europe is foreseen to be given for the first time next year. The International Award Committee for European Chemistry Gold Medal (IACM) will carefully examine received nominations for the Award and propose an awardee to the EuCheMS Executive Board.

    The nominations can be submitted by EuCheMS Member Organisations, EuCheMS Professional Networks or individual members through the on-line nomination form available at http://www.euchems.eu/awards/european-chemistry-gold-medal/

    Deadline: 15 May 2017

2016 EuCheMS Yearbook is available

You are kindly invited to read through the 2016 EuCheMS Year Book, which is now available on-line at http://www.euchems.eu/wp-content/uploads/2017/03/170331-EUCHEMS-yearbook-2016.pdf

News from the Spanish Society of Medicinal Chemistry (SEQT)

The Spanish Society of Medicinal Chemistry (SEQT) has the pleasure to invite you to join the 4th SEQT YOUNG RESEARCHERS SYMPOSIUM 2017. The meeting will take place at the Parc Cientific (Barcelona) the 17thof June 2016.
Abstract submission and registration is now open!

At this event, young scientists (Master and PhD students as well as Postdocs) will have the opportunity to present their work in the form of oral or poster presentations.

Scientific Programme:

  • Plenary lecture: Marc Martinell (Cofounder and CEO of Mynoryx)
  • Scientific keynote lecture: Marc Vendrell (Univ. Edimburgh): "A journey of 10 years making chemical imaging probes"
  • Round table: ‘Which is the role of Medicinal Chemist in Drug Discovery?" Carme Almansa (Esteve), Rodolfo Lavilla (UB), Marc Vendrell (Univ. Edimburgh), Roberto Chicharro (Juste).

Call for abstracts and registration:

Deadline for abstract submission: 21 April 2017
Deadline for registration: 28 April 2017

For further information and regular updates, please visit our website http://www.seqt.org/en/events/young-research-symposium/

News from the Division Medicinal Chemistry, Royal Netherlands Chemical Society (KNCV)

On March 17th, 2017 the Division Medicinal Chemistry of the Royal Netherlands Chemical Society awarded Dr Marcel Scheepstra out of 8 nominees the two-yearly Medicinal Chemistry Prize for the best Dutch Ph.D. thesis in the discipline.

DR MARCEL SCHEEPSTRA WINS THE DUTCH MEDICINAL CHEMISTRY PRIZE 2015-2016

On March 17th, 2017 the Division Medicinal Chemistry of the Royal Netherlands Chemical Society awarded Dr. Marcel Scheepstra out of 8 nominees the two-yearly Medicinal Chemistry Prize for the best Dutch Ph.D. thesis in the discipline. The title of his thesis is ‘Molecular modulation of nuclear receptor conformational states’. The research was performed at the Eindhoven University of Technology in the group of prof. dr. Luc Brunsveld and dr. Lech Milroy, and resulted in several exceptionally high quality papers in for example, Nature Communications, ACS Chemical Biology and Angewandte Chemie.

The jury of the prize consisted of prof. dr. Pieter Van der Veken (University of Antwerp), dr. Gary Tresadern (Janssen Pharmaceutica R&D, Toledo), dr. Laura Heitman (Leiden University) and dr. Leon van Berkom (Mercachem). The prize - € 1000, an art work and a certificate - was handed over during the spring symposium in Utrecht entitled ‘Small molecules and biologicals in cancer immunotherapy’ (125 attendees), where dr. Marcel Scheepstra presented the winning work. His Ph.D. title was obtained in September 2016 and he now is employed as Senior Scientist in the department Medicinal Chemistry at Mercachem, The Netherlands.

 

 Chairman Prof. Dr Roland Pieters hands over the award to winner Dr Marcel Scheepstra (left)

 

 Award winner Dr Marcel Scheepstra, chairman Prof. Dr Roland Pieters (left) and secretary Dr Peter Molenveld of sponsor Mercachem (right).

News from the Biological and Medicinal Chemistry Sector (BMCS) of the Royal Society of Chemistry (RSC)

The Royal Society of Chemistry Biological and Medicinal Chemistry Sector is proud to announce the winners of the Malcolm Campbell Memorial Prize for 2017 as well as two upcoming events:

  • Transport of Delight? The 2nd Symposium on Transporters in Drug Discovery and Development, May 15-16, 2017 - Burlington House, Piccadilly, London
  • Medicinal Chemistry for World Health 2, June 18-20, 2017 - Tres Cantos, Spain

Malcolm Campbell Memorial Prize 2017: Announcement of Winners

The Royal Society of Chemistry Biological and Medicinal Chemistry Sector is proud to announce the winners of the Malcolm Campbell Memorial Prize for 2017. The prize has been awarded to Sam Butterworth, Darren Cross, Ray Finlay, Richard A Ward and Michael J Waring for contributions to the team that discovered TAGRISSO(TM) (osimertinib, AZD9291) at AstraZeneca.

Osimertinib, a potent, oral, CNS-active, irreversible epidermal growth factor receptor (EGFR) inhibitor that was developed specifically for the treatment of patients with T790M mutation positive NSCLC, has demonstrated significant clinically meaningful improvement in efficacy compared to standard of care chemotherapy in these patients, with fewer serious adverse events.  In record time, just 2 years and 9 months after the first patient was dosed, osimertinib was provisionally approved for patients whose tumours have a specific epidermal growth factor receptor (EGFR) mutation (T790M) and whose disease has progressed due to resistance to other EGFR-blocking therapy.

The BMCS Committee wishes to express its gratitude for the high-quality entries from both academia and industry for the 2017 award.

The Malcolm Campbell Memorial prize commemorates Professor Campbell’s outstanding contributions in a broad range of chemistry and their applications to the understanding of bioactivity.  The prize will be presented formally to the winning team during the 19th RSC / SCI Medicinal Chemistry Symposium to be held at Churchill College in Cambridge on 10th - 13th September 2017.

TRANSPORT OF DELIGHT? The 2nd Symposium on Transporters in Drug Discovery and Development, May 15-16, 2017 - Burlington House, Piccadilly, London

Call for poster abstracts will close on 31st March 2017

Cell surface transporters play a key role in human health and disease, both through their impact on drug disposition and as therapeutic targets in their own right.   This meeting continues on from the first, successfully held in 2014, and is anticipated to become part of a regular series. It should be of interest to medicinal chemists, DMPK scientists and other workers with interests on the impact of transporters on human health

Website: www.maggichurchouseevents.co.uk/bmcs 


Medicinal Chemistry for World Health 2,
June 18-20, 2017 - Tres Cantos, Spain

The call for posters will close on 21st April

Bringing together leading exponents for an exciting spread of themed sessions, the meeting will appeal to anyone with an interest in drug discovery and medicinal chemistry. With great opportunities for collaborative academic–industrial partnerships and open innovation discovery programmes, researchers from both sectors will benefit from the networking opportunities that the meeting will also offer.

Website:  http://www.rsc.org/events/detail/23938/2nd-symposium-on-medicinal-chemistry-for-world-health

 

MedChemComm

 

ISSUE SPONSORED BY


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EFMC ORGANISED EVENTS

April 23-26, 2017
Oegstgeest, The Netherlands
13th EFMC Short Course on Medicinal Chemistry

June 25-28, 2017
Philadelphia (Sheraton Downtown), USA
ACSMEDI-EFMC: Medicinal Chemistry Frontiers 2017

August 31 - September 1, 2017
Vienna, Austria
EFMC-YMCS 2017 4th EFMC Young Medicinal Chemist Symposium

EFMC SPONSORED EVENTS

June 11-14, 2017
Copenhagen, Denmark
1st RSC Anglo-Nordic Medicinal Chemistry Symposium

June 25–28, 2017
Dubrovnik (Srebreno), Croatia
10th Joint Meeting on Medicinal Chemistry

September 25-28, 2017
Kazan, Russia
3rd Russian Conference on Medicinal Chemistry

January 28 - February 1, 2018
St Anton, Austria
1st Alpine Conference on Medicinal and Synthetic Chemistry

EFMC SPONSORED SCHOOLS

June 11-16, 2017
Loughborough, UK
Medicinal Chemistry Residential School

September 18-20, 2017
Rimini, Italy
Summer School in Pharmaceutical Analysis (SSPA)

JOB PORTAL

29/03/2017  PhD position in drug design, Academic Medical Centre Amsterdam - Cardiovascular Research Institute Maastricht: Biochemistry, Maastricht - Amsterdam, The Netherlands - Read more

16/03/2017  Scientist/Senior Scientist, Evotec (UK) Ltd: Discovery Chemistry, Abingdon, United Kingdom - Read more

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