MedChemWatch
Monthly Newsletter September 2017

JOIN THE EFMC COMMUNICATION TEAM!

The European Federation for Medicinal Chemistry (EFMC) invites young and motivated medicinal chemists or chemical biologists to volunteer for its communication team, to help develop, feed and monitor its presence on social media (Twitter, LinkedIn & Facebook).

This is an opportunity for you to be informed of the latest scientific trends and events, develop an extensive network across the community, strongly increase your visibility and awareness of the many opportunities offered by the EFMC… and it comes with a travel grant to the EFMC main symposium!

The members of the EFMC communication team are responsible for the execution of a professional and relevant social media content, and to develop a plan to boost community engagement and EFMC brand awareness. The social media strategy will be elaborated with the EFMC executive committee.

What can you contribute?

  • Help develop and implement the social media and content strategy, to extend the EFMC social media presence and engage the community.
  • Contribute to the editorial calendar.
  • Develop a strategy for social listening and community engagement in order to join and drive the conversation on various social media platforms.
  • Collaborate with experts in the community to create the contents of original tweets and posts.

Interested in joining the team?

Contact the EFMC Administrative Secretariat by December 1, 2017: administration@efmc.info

EFMC PRIZES AT THE EFMC-ASMC ’17

The « EFMC Prize for a Young Medicinal Chemist in Academia » and the « EFMC Prize for a Young Medicinal Chemist in Industry » have been established by the European Federation for Medicinal Chemistry (EFMC) to acknowledge and recognise outstanding young medicinal chemist workings in European academia and industry within.

The prizes are given annually and consist of a diploma, 1.000€ and an invitation to give a short presentation at an EFMC Symposium. Two runners-up are also duly acknowledged.

The 2017 Prizes have been conferred on occasion of the 7th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC), held in Vienna on August 27-31, 2017.

The winner of the Industry Prize was Philip Humphreys (GlaxoSmithKline, UK). He gave a talk on the “Development of non-BET Bromodomain Chemical Probes”. The most meritorious runners-up were Fabien Lecomte (UCB, UK) and Mirjana Bukvic (Fidelta, Croatia).

Christian Gruber (Medical University of Vienna, Austria) won the 2017 EFMC Prize for a Young Medicinal Chemist in Academia. At the EFMC-ASMC Symposium, he gave a talk entitled “Nature-Derived Peptides as Pharmacological Tools to Design Novel Therapeutics“. Andreas Koeberlee (Friedrich-Schiller-University Jena, Germany) and Vittorio Limongelli (USI Lugano, Switzerland) have been identified and acknowledged as runners-up.

EFMC ROCHE STUDENTSHIPS

One of the goals of the EFMC is to enhance interactions at the industry/academia interface and to promote improved cooperation between the pharmaceutical industry and academia. In the spirit of cross-sector cooperation and collaboration, EFMC and F. Hoffman-La Roche have teamed up to create an award for students based in European universities and recognise excellence accomplished during internships in industry. 

The fifth EFMC-Roche studentships have been announced by Koen Augustyns (EFMC) and Rainer Martin (F. Hoffmann-La Roche) at the 7th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC’17),

The recipients were Eleen Laul (University of Edinburgh/MRC Centre for Inflammation, UK) and Xinlan Aloise Cook (University of York, UK). We would like to congratulate both of them for their fantastic achievement.

EFMC would like to thank F. Hoffman-La Roche for its contribution and support.

To find more about the EFMC Prizes and studentships, we invite you to visit the EFMC website www.efmc.info

EFMC BEST POSTER PRIZE AT EFMC-ASMC’17

5 EFMC Best Poster Prizes have been granted during the 7th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry (EFMC-ASMC’17).

The EFMC Best Poster Prizes have been granted to the following participants:

P116 - METFORMIN AND THE CATALYTIC ACTIVITY OF SHIP2
Mika Berg (University of Helsinki, Finland)

P135 - STEREOSELECTIVE ORGANOCATALYZED SYNTHESIS OF α-FLUORO β-AMINO AND α-FLUORO γ-NITRO THIOESTERS
Elena Cosimi (ETH Zürich, Switzerland)

P207 - NEW PERSPECTIVES IN SEROTONERGIC SIGNAL TRANSDUCTION STUDIES. 3-(1-ALKYL-1H-IMIDAZOL-5-YL)-1H-INDOLES, POWERFUL TOOLS TO STUDY THE 5-HT7 RECEPTOR FUNCTION
Adam S. Hogendorf (Institute of Pharmacology, Poland)

P316 - GOLD-MEDIATED BIOORTHOGONAL DEPROTECTION OF A SPECIFICALLY-DESIGN ANTICANCER CODRUG
Belen Rubio Ruiz (University of Edinburgh, United Kingdom)

P353 - USING 3D-PHARMACOPHORES TO DESIGN NEW EZH2 INHIBITORS
Filipa Ramilo-Gomes (Universidade de Lisboa, Portugal)

 

EFMC-YMCS PRIZES 2017

The 2017 EFMC-YMCS Prizes have been awarded during the 4th Young Medicinal Chemist Symposium (EFMC-YMCS), held in Vienna on August 31-September 1, 2017.

Daniel MERK (ETH ZÜRICH, Switzerland) received the EFMC-YMCS Presentation Prize for his presentation on the "Facing Non-Alcoholic Steatohepatitis with Multitarget Compounds". The prize was awarded by Koen Augustyns - EFMC President on behalf of the prize sponsors EFMC & Idorsia.

The Presentation Prize covers:

- An oral communication and free registration for the next EFMC-ISMC 2018 in Ljubljana in Summer 2018 (sponsored by the EFMC)

- A travel grant of up to 1000€ to visit EFMC-IMSC 2018 (sponsored by Idorsia)

Matthieu PLACE (ICOA CNRS, France) received the EFMC-YMCS Poster Prize for his presentation on "Design of Novel Imidazopyridazines as Strong Haspin Inhibitors". The prize was awarded by Thierry Langer on behalf of the prize sponsors MedChemCom and Molecules. The Prize consists of a diploma, a 500€ cash prize offered Molecules and an e-subscription to MedChemComm.

Vittorio PACE (University of Vienna, Austria) was awarded the EFMC-YMCS Public's Choice Prize for his presentation on "Building-up Molecular Complexity with Carbenoids: New Vistas in Homologation Chemistry". The prize, based on the votes of YMCS participants, was awarded by Cosimo Dolente (F. Hoffman-La Roche) on behalf of the prize sponsor F. Hoffman-La Roche. The Prize consists of a diploma and an iPad.

2018 IUPAC-RICHTER PRIZE – CALL FOR NOMINATIONS

IUPAC and Gedeon Richter, Plc. are pleased to announce the 2018 IUPAC-Richter Prize in Medicinal Chemistry. The Prize was established in 2006 by a generous gift from the Chemical Works of Gedeon Richter, Plc. (Budapest, Hungary) to acknowledge the key role that medicinal chemistry plays toward improving human health. The prize  – USD 10000 – is to be awarded to an internationally recognised scientist, preferably a medicinal chemist, whose activities or published accounts have made an outstanding contribution to the practice of medicinal chemistry or to an outstanding example of new drug discovery.

The 2018 IUPAC-Richter Prize will be presented during the 36th National Medicinal Chemistry Symposium (29 April – 2 May 2018) on Medicinal Chemistry in Nashville, Tennessee (USA), where the recipient will also give a plenary lecture on the subject of his/her research.

Applications should be received by NOMINATION only, with just one person needing to serve in that capacity, although a total of five (5) individuals should be listed as referees overall. The package must be submitted electronically and should contain :

  • a complete resume
  • a professional autobiography of not more than two page
  • a one-page summary of what the individual considers to be his/her activities, accomplishments and/or publications that have had the most significant impact upon the field of Medicinal Chemistry

The material will be forwarded confidentially to an independent selection committee appointed by the IUPAC Subcommittee on Drug Discovery and Development.

Nomination materials should be submitted by 15 December 2017 through this Nomination Form.

For further information please contact Professor Janos Fischer, Chair of the IUPAC Subcommittee on Drug Discovery and Drug Development, by email at j.fischer@richter.hu.

NEWS FROM THE FRENCH MEDICINAL CHEMISTRY SOCIETY (SCT)

The SCT is pleased to announce the following meeting:

Chemical Biology, Contribution to Molecular Therapeutic Innovation: Conjugates and Drug Discovery Chemistry, new challenges for targeted therapies

December 7, 2017, Paris, France

Website: http://www.sct-asso.fr/fall_one_day_symposium.html

The aim of the symposium is to illustrate the great potential and the applications of conjugates in contributing to therapeutic innovation.
This meeting is dedicated to a large audience of organic and medicinal chemists, biochemists and biologists, and covers recent advances in the field of conjugates for therapeutic approaches, focusing on their preparation, evaluation and applications.
Recent development of conjugates offers new promises for the treatment of various diseases. In oncology, two antibody-drug conjugates (brentuximab vedotin and trastuzumab emtansine) are already approved for clinical use, and numerous conjugates are still in clinical evaluation. In addition to antibodies, other classes of vehicles like proteins, peptides, vitamins and polymers have been investigated for the selective delivery of drugs to malignant tissues. Conjugates also emerge for the development of new vaccines or appear as powerful tools to explore or manipulate living systems in chemical biology approaches.

NEWS FROM THE BIOLOGICAL AND MEDICINAL CHEMISTRY SECTOR (BMCS) OF THE ROYAL SOCIETY OF CHEMISTRY (RSC)

The BMCS is pleased to announce the following meetings:

2nd RSC / SCI Fibrosis Medicinal Chemistry conference
10th November 2017, SCI, London, UK

Recent Trends and Technologies in Medicinal Chemistry towards Medicines of the Future
Friday 8th December 2017, Society for Medicines Research, London, UK

2nd RSC / SCI Fibrosis Medicinal Chemistry conference

10th November 2017, SCI, London, UK

The last day for early-bird registrations is 29th September

Website:  http://www.rsc.org/events/detail/27671/2nd-sci-rsc-fibrosis-medicinal-chemistry-symposium

Synopsis:  Fibrosis disease is the result of a dysregulated wound healing process and is responsible for considerable patient mortality affecting multiple organs in diseases such as idiopathic pulmonary fibrosis (IPF), diabetic nephropathy, steatohepatitis and systemic sclerosis. Fibrosis disease pathology is often complex and this inaugural symposium on fibrosis will provide mechanistic insight and progress in medicinal chemistry and drug discovery from experts across the world

Recent Trends and Technologies in Medicinal Chemistry towards Medicines of the Future

Friday 8th December 2017, Society for Medicines Research, London, UK

Website: http://www.rsc.org/events/detail/27399/recent-trends-and-technologies-in-medicinal-chemistry-towards-medicines-of-the-future

Synopsis:  This one day symposium will highlight some of the new technologies and research trends at the forefront of drug discovery today through an expert speaker cohort of scientists from Pharma, biotech, academia, public sector and charitable institutions from across the UK.

The latest edition of MedChemComm, the official journal of the EFMC, is available at:

MedChemComm

 

EFMC ORGANISED EVENTS

September 6-7, 2018
Ljubljana, Slovenia
5th EFMC Young Medicinal Chemist Symposium (EFMC-YMCS 2018)

EFMC SPONSORED EVENTS

January 28 - February 1, 2018
St Anton, Austria
1st Alpine Conference on Medicinal and Synthetic Chemistry

JOB PORTAL

Early Stage Researcher in Medicinal Chemistry, University of Basel (UNIBAS), University of Utrecht (UU), PamGene: Department of Pharmaceutical Sciences (UNIBAS), Department of Chemical Biology & Drug Discovery (UU), Basel, Utrecht, 's-Hertogenbosch, Switzerland
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Early Stage Researcher in Medicinal Chemistry, University of Ljubljana (UL), University of Utrecht (UU), PamGene: Faculty of Pharmacy, Chair of Pharmaceutical Chemistry (UL), Department of Chemical Biology & Drug Discovery (UU), Ljubljana, Utrecht, 's-Hertogenbosch, Slovenia
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Early Stage Researcher in Medicinal Chemistry, University of Utrecht (UU), University of Ljubljana (UL), PamGene: Department of Chemical Biology & Drug Discovery (UU), Faculty of Pharmacy, Chair of Pharmaceutical Chemistry (UL), Utrecht, Ljubljana, 's-Hertogenbosch, The Netherlands
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Early Stage Researcher in Medicinal Chemistry, University of Basel (UNIBAS), University of Ljubljana (UL): Department of Pharmaceutical Sciences (UNIBAS), Faculty of Pharmacy, Chair of Pharmaceutical Chemistry (UL), Basel, Ljubljana, Switzerland
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Early Stage Researcher in Medicinal Chemistry, University of Ljubljana (UL), Lund University (ULUND), SARomics, Red Glead: Faculty of Pharmacy, Chair of Pharmaceutical Chemistry (UL), Department of Chemistry (ULUND), Ljubljana, Slovenia
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Early Stage Researcher in Medicinal Chemistry, Università degli Studi di Milano (UMIL), Universiteit Utrecht (UU), PamGene: Chemistry (UMIL), Department of Chemical Biology & Drug Discovery (UU), Milano, Utrecht, 's-Hertogenbosch, Italy
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Early Stage Researcher in Medicinal Chemistry, Università degli Studi di Milano (UMIL), Université Grenoble Alpes (UGA), Centre national de la recherche scientifique (CNRS-Glycopedia): Chemistry (UMIL), CERMAV (UGA), Milano, Gières, Grenoble, Italy
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Early Stage Researcher in Medicinal Chemistry, Université Grenoble Alpes (UGA), Universiteit Utrecht (UU), PamGene: CERMAV (UGA), Department of Chenical Biology & Drug Discovery (UU), Gières, Utrecht, 's-Hertogenbosch, France
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Early Stage Researcher in Medicinal Chemistry, Universiteit Utrecht (UU), Université Grenoble Alpes (UGA), Centre national de la recherche scientifique (CNRS): Department of Chemical Biology & Drug Discovery (UU), CERMAV (UGA), Utrecht, Gières, Grenoble, The Netherlands 
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Early Stage Researcher in Medicinal Chemistry Université Grenoble Alpes (UGA), Università degli Studi di Milano (UMIL), Centre national de la recherche scientifique (CNRS) : CERMAV (UGA), Department of Chemistry (UMIL), Gières, Milano, Grenoble, France
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Research / Senior Scientist Medicinal Chemistry, UCB: Medicinal Chemistry, Braine-L'Alleud, Belgium
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Principal Scientist Medicinal Chemistry, UCB: Medicinal Chemistry, Braine-L'Alleud, Belgium
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Medicinal / Synthetic Organic Chemists, Concept Life Sciences: Drug Discovery, Sandwich, Kent, United Kingdom
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