Hit generation is a crucial step in the drug discovery process. Accessing high quality hits will greatly increase the speed and chance of success to identify drug candidates.
In this third webinar by the EFMC Best Practices in Medicinal Chemistry Working Group, we present current approaches to generate and validate hits. We also highlight the importance of having an integrated strategy combining several approaches.
We hope this will help students, early career professionals as well as experienced researchers to get an overview of possible approaches and how to design a successful hit generation campaign. In addition, this may serve to enrich teaching material at universities and companies.
The webinar is accompanied with a case study from the recent literature highlighting several hit generation strategies.