The European Federation for Medicinal Chemistry (EFMC) is an independent association representing medicinal chemistry societies in Europe. Its objective is to advance the science of medicinal chemistry by promoting cooperation and networking, by providing training and mentoring, by rewarding scientific excellence, and by facilitating communication and influencing stakeholders.

Meetings  July 2018 Next
  • 14th EFMC Short Course on Medicinal Chemistry - Peptide Therapeutics: Inspiring Beacon of Hope for the Pharmaceutical Future

    April 22-25, 2018   Oegstgeest (near Leiden), The Netherlands

    This intensive course is intended for scientists working in the field, and the presentations will be given by senior scientists from industry and academia. The number of participants is limited to 35, to allow in depth discussion. Should the number of applications exceed the maximum, preference will be given to applicants from EFMC adhering countries and employees of EFMC corporate members. Upon special request to the organisers, only based on financial conditions and supported by an argued recommendation of the head of the department of the applicant, up to 3 applicants from academia may be admitted at a reduced fee.

    Course Outline

    Peptides are a gigantic class of bioactive compounds, offering an immense chemical diversity as well as the potential for finding and characterizing new targets and also for developing non-peptidic ‘analogues’. However, the development of peptides into clinically useful pharmaceuticals is full of challenges including their pharmacokinetic  properties (short biological half-life, lack of oral bioavailability, difficulties to reach intracellular or intranuclear targets) as well as their conformational flexibility which may cause reduced affinity and selectivity. However, recent developments in discovery, manufacturing and formulation, as well as in preclinical and clinical development, has triggered a lasting resurrection of pharmaceutical interest in peptide therapeutics.

    This EFMC seminar will bring together enthusiastic, approachable experts, both from academia and industry, on selected hot aspects in the discovery and development of peptide therapeutics. Real life examples and interactive discussions will give the participants a unique opportunity to learn in a short time how the challenges in peptide therapeutics can be handled and overcome.

    Course Organiser
    Bart DE SPIEGELEER (Ghent University, Belgium)
    Local Organiser
    Henk TIMMERMAN (VU University Amsterdam, The Netherlands)

    Contact person: Prof. Dr. Henk Timmerman
    Tel: +31 71 5762791

    Organised by : European Federation for Medicinal Chemistry (EFMC)
    Organised by : Section Medicinal Chemistry, Royal Netherlands Chemical Society (KNCV) (The Netherlands)

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