The European Federation for Medicinal Chemistry (EFMC) is an independent association representing medicinal chemistry societies in Europe. Its objective is to advance the science of medicinal chemistry by promoting cooperation and networking, by providing training and mentoring, by rewarding scientific excellence, and by facilitating communication and influencing stakeholders.

Meetings  November 2018 Next
  • Protein-Protein Interactions 2019

    April 4-5, 2019   Leeds, United Kingdom

    Virtually all vital cellular processes are controlled by protein-protein interactions (PPIs), including gene expression, proliferation, intracellular communication and apoptosis. The understanding and manipulation of PPIs therefore plays an important role in fathoming the biology of healthy and diseased states. Achieving this goal will lead to new probes of cell signalling pathways or systems biology, and molecular therapeutics for addressing unmet medical need.

    To date, only a few PPIs have been the subject of drug discovery initiatives by the pharmaceuticals industry. Given the potential opportunities around modulating more of the estimated >650,000 PPIs, this field continues to generate considerable scientific interest, which has stimulated significant academic and industrial innovation. This meeting will address recent advances in the area. Topics will include: inducing protein degradation using small molecules, protein engineering and synthetic biology, integration of computational and experimental methods to study PPIs, characterisation and identification of new PPI inhibitors and lead optimization challenges for molecules targeting PPIs from case studies in drug discovery.Speakers from both industry and academia will describe strategies for addressing these challenges whilst showcasing the opportunity for creativity and innovation.

    Confirmed Speakers

    • Prof Craig Crews, Yale University, United States
    • Prof Amy Keating, Massachusetts Institute of Technology, United States
    • Dr Isabelle Landrieu, Universite de Lille, France
    • Dr Angelita Rebollo, Centre d'Immunologie et des Maladies Infectieuses, France
    • Dr Graeme Robb, AstraZeneca, United Kingdom
    • Prof Ali Tavassoli, University of Southampton, United Kingdom
    • Prof Dek Woolfson, University of Bristol, United Kingdom

    For more information: SCI Conferences Team
    Tel: +44 (0)20 7598 1561
    Email: conferences@soci.org

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