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December 10-11, 2019
Veldhoven, The Netherlands

Contact person: Dr Ingrid Dijkgraaf
Tel: +31 43 3881681
Fax: +31 43 3884159
Email:

December 11, 2019
Paris, France

Contact person: Dr Brigitte LESUR
Tel: +33 (0) 1 55 72 26 16
Email: or

Organised by:
  • Société de Chimie Thérapeutique (France)

December 11, 2019
Paris, France

The French Society of Medicinal Chemistry (Société de Chimie Thérapeutique – SCT) is pleased to invite you to Paris, on December 11th, 2019 for the 4th one-day thematic symposium focusing on the contribution of Chemical Biology to Molecular Therapeutic Innovations.

The aim of the symposium is to illustrate the great potential and applications of RNA-targeting modalities in contributing to therapeutic innovation.
This meeting is dedicated to a large audience of organic and medicinal chemists, biochemists and biologists from academic and industry. During this day, we will focus on recent advances in the field of RNA targeting using small molecules as well as oligonucleotides: the synthetic challenges involved in the design of RNA-targeting agents and on the validation of relevant RNA targets, as well as on the current methodologies used to study RNA/ligands interactions. RNA has already been drugged. Ribosomal RNA was drugged serendipitously with natural product antibiotics and later linezolid. A design-driven approach to drugging RNA was achieved with antisense oligonucleotides (ASOs) and then by RNA interference (RNAi) mechanisms.
More recently, small molecules that bind to the FMN riboswitch and to SMN2 pre-mRNA were reported and are close to clinical application. All those recent developments in the field of RNA-targeting definitely hold promise for future therapeutic applications.

Confirmed Speakers:

  • Matthew DISNEY (Scripps, Florida, USA)
    Translating RNA Sequence Into Lead Small Molecule Medicines
  • Maria DUCA (Université Côte d’Azur, France)
    Synthetic Small-Molecule RNA Ligands : Scope and Applications
  • Mélanie ETHEVE-QUELQUEJEU (Université de Paris, France)
    Modified RNAs as Molecular Tools for Structural and Functional Studies of RNAs dependents Enzymes
  • Eric ENNIFAR (Université de Strasbourg, France) 
    Structure-Guided Discovery of Novel Ligands Targeting the HIV-1 Genomic Viral RNA
  • Jonathan HALL (ETH Zürich, Switzerland)
    A Bright Future for Oligonucleotide Drugs
  • Gerhard MUELLER (Gotham Therapeutics, Germany)
    Epitranscriptomic Readers, Writers, and Erasers: a Biophysics and Medicinal Chemistry Perspective
  • Alleyn PLOWRIGHT (Sanofi-Aventis Deutschland GmbH, Germany)
    Modulating RNA - Recent Drug Discovery Approaches and Opportunities for Diverse Modalities
  • Helene TRAN (Servier Research Institute, France)
    Antisense Oligonucleotides Therapeutics for CNS Disorders

For more information please contact: secretariat@sct-asso.fr

December 13, 2019
Cambridge, United Kingdom

The Biological and Medicinal Chemistry Sector (BMCS) of the RSC will be hosting its 13th postgraduate symposium for PhD students and postdoctoral workers researching in biological or medicinal chemistry and related areas. The event will be held in the Department of Chemistry at the University of Cambridge on Friday 13th December 2019. Researchers working in these areas are invited to participate. Registration will start at 9:00 am with talks beginning at 10:00 am. The day will consist of 11 oral presentations (8 student and 3 keynote) plus a Flash Poster section. Each 20 minute student talk will be followed by 10 minutes for questions.

Throughout the day there will be keynote talks from industrial and academic chemists. A buffet lunch will be provided to accompany the poster session. The BMCS judges will be awarding prizes to participants. There will be prizes of £500 for the best oral presentation and of £250 for the best poster and these will be celebrated at the end of the day.

If you are interested in presenting your relevant PhD or post-doctoral work please submit a half-page abstract by 17th September 2019 in addition to registering. Those selected by the BMCS committee to give oral presentations will be notified by 27th October. Travel expenses will be reimbursed to all speakers.

This event is FREE but all attendees should register as soon as possible and no later than by Saturday, 30th November 2019.

Online registration form: http://bit.ly/2Ui6Eqd

For queries and abstract submission contact Dave Alker at dave.alker@btinternet.com